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Jan 16, 2021 · A new probe that features excimer formation has been designed to detect cancer-related biomarker alkaline phosphatase(ALP) and presents good biocompatibility with negligible cytotoxicity and displays remarkable cell imaging functions, which allows for its application in biosystems.

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Apr 11, 2019 · Hydrogen-deuterium exchange mass spectrometry is applied to probe the conformational dynamics of human SERT in the absence and presence of known substrates and targeted drugs to provide a comprehensive direct view of the conformations of SERT upon binding both biologically relevant substrate/ions and ligands of pharmaceutical …

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